Health

Calculate safe oral and IV potassium replacement parameters for hypokalemia. Oral 20–40 mEq/dose (120 mEq/day); IV peripheral ≤ 10 mEq/h (40 mEq/L); IV central ≤ 20 mEq/h (80 mEq/L); daily IV cap 240 mEq. IV KCl must be on an infusion pump — never IV push. Correct hypomagnesemia first. Derived from Gennari NEJM 1998, Cohn 2000, Kraft 2005, MDCalc, and Asmar 2023. Not medical advice.

Health

Calculate the Reticulocyte Production Index (RPI) to judge whether the marrow is responding appropriately to anemia. Step 1 — corrected reticulocyte count CRC = Retic% × (patient Hct / normal Hct) (normal Hct 45% men, 40% women). Step 2 — maturation (shift) factor (days) varies with Hct: 45%→1.0, 35%→1.5, 25%→2.0, 15%→2.5 (linearly interpolated). Step 3 — RPI = CRC / maturation factor. Interpretation: RPI > 2 (especially ≥ 3) → appropriate marrow response, suggesting hemolysis or recovery from acute blood loss (the marrow is working — look for peripheral loss/destruction); RPI < 2 → hypoproliferative anemia (iron deficiency, anemia of chronic disease/inflammation, aplastic anemia, renal anemia, MDS, marrow infiltration, untreated megaloblastic anemia). RPI is less reliable when anemia is changing rapidly; if an absolute reticulocyte count (ARC, ×10⁹/L) is available, prefer it. Based on Hillman & Finch, Berlin Blood 1959, and MDCalc. Not medical advice.

Health

Calculate the COMPLETE (post-endoscopy) Rockall score for acute upper gastrointestinal hemorrhage (AUGIB) to predict rebleeding and mortality. Five parameters: Age (<60 =0, 60–79 =1, ≥80 =2); Shock (none SBP≥100 & HR<100 =0, tachycardia SBP≥100 & HR≥100 =1, hypotension SBP<100 =2); Comorbidity (none =0, other major =2, renal/liver failure or disseminated malignancy =3); Endoscopic diagnosis (Mallory-Weiss or no lesion/stigmata =0, all other =1, upper GI malignancy =2); Stigmata of recent hemorrhage (none or dark spot only =0, blood/adherent clot/visible vessel =2). The first three parameters alone form the PRE-ENDOSCOPIC score (0–7); all five form the COMPLETE score (0–11). Interpretation: ≤2 low risk (~4.9% rebleeding, ~0% mortality — consider early discharge); ≥5 high risk. Derived from Rockall et al. 1996 (Gut). The Glasgow-Blatchford Score better identifies very-low-risk patients. Not medical advice.

Development

Analyze Cache-Control directives, calculate browser/shared-cache TTL and stale budgets, detect directive conflicts, and compare static behavior notes for generic HTTP, Fastly, Cloudflare, and Akamai.

Audio Tools

Use local HT-Demucs source separation to export vocals, a mixed instrumental, or both in a ZIP.

Cryptography

Decode WebAuthn/FIDO2 assertion fields, inspect authenticatorData flags and signCount, check challenge/origin/rpIdHash binding, and optionally verify ES256, RS256, or Ed25519 signatures with a supplied COSE public key.

Health

Categorize renal function from creatinine clearance (CrCl) and provide FDA/KDIGO-aligned dosing guidance: Normal (CrCl ≥60) → standard dosing; Mild (30–59) → consider dose reduction or interval extension; Moderate (15–29) → reduction and/or extension typically required; Severe (<15) → significant reduction, many drugs contraindicated or post-dialysis only. Outlines two adjustment strategies: (A) interval extension for concentration-dependent drugs (aminoglycosides, vancomycin), (B) dose reduction for time-dependent drugs (β-lactams). Dialysis toggle flags the need for post-dialysis supplementation per the specific drug label. Derived from FDA Pharmacokinetics Guidance, the KDIGO Drug Dosing Consensus, and NIDDK guidance. This tool does NOT replace the FDA-approved package insert for any specific drug. Not medical advice.

Health

Calculate the continuous IV infusion rate that maintains a target steady-state plasma concentration: R₀ = Css · CL, where Css is the target concentration and CL is clearance. At steady state, the infusion rate equals the elimination rate. If the IV solution concentration (mg/mL) is provided, the tool additionally derives the infusion-pump delivery rate in mL/h, which is what the pump is actually set to in clinical practice. This is an IV-only tool — bioavailability F is not applicable. Reaching steady state requires approximately 4–5 half-lives. Not medical advice.

Health

Estimate a pediatric drug dose using one of four methods: (1) Young's rule (age-based) — Child dose = Adult dose × age / (age + 12); (2) Clark's rule (weight in pounds) — Child dose = Adult dose × weight(lb) / 150; (3) mg/kg per-weight regimen (the modern first-line method) — Child dose = dosePerKg × weight(kg); (4) BSA method (Mosteller) — Child dose = Adult dose × BSA_child / 1.73, with BSA = √(height·weight/3600). These are empirical approximations; modern practice prefers drug-specific mg/kg or mg/m² regimens derived from pediatric trials and verified against pediatric references and the approved labeling. Not medical advice.

Web & Internet

Search the web through the s.stdlang.com SearXNG instance and return its JSON response for automation or downstream tools.

Video Processing

Create a preview montage from 5-10 evenly spaced video clips without re-encoding.

Text Processing

Deterministically analyze, replace, remove, or duplicate English vowels and consonants with position statistics and an audit trail.