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Maintenance Fluid Rate (4-2-1 Rule)

· Last updated:2026-08-10

This tool is for informational purposes only and does not constitute medical, financial, or legal advice; consult a qualified professional for advice.

Calculate the hourly maintenance fluid rate using the Holliday-Segar 4-2-1 rule: first 10 kg at 4 mL/kg/h, next 10 kg at 2 mL/kg/h, each kg above 20 at 1 mL/kg/h. Also shows the 24-hour total and the 100/50/20 mL/kg/day daily method for cross-checking. Weight in kg or lb (auto-converted). Derived from Holliday-Segar Pediatrics 1957, MDCalc, and Meyers 2009. Not medical advice.

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Written by the Elysia Tools team

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Key facts

Category
Health
Input types
number, select
Output type
json
Sample coverage
4
API ready
Yes

Overview

Calculate an hourly maintenance fluid rate with the Holliday-Segar 4-2-1 rule. Enter weight in kilograms or pounds to see the rate in mL/h, the estimated 24-hour total, and a 100/50/20 mL/kg/day cross-check. This calculator is an estimate, not medical advice.

When to use

  • Estimate maintenance fluid requirements for a patient who is fasting or unable to take fluids orally.
  • Check a pediatric or adult maintenance infusion rate using the 4-2-1 rule.
  • Compare the hourly 4-2-1 estimate with the 100/50/20 mL/kg/day method.

How it works

  1. 1Enter the patient's body weight.
  2. 2Select kg or lb; weight entered in pounds is converted to kilograms.
  3. 3The calculator applies 4 mL/kg/h for the first 10 kg, 2 mL/kg/h for the next 10 kg, and 1 mL/kg/h above 20 kg.
  4. 4Review the hourly rate, 24-hour total, patient category, and daily-method cross-check in the JSON result.

Use cases

  • Pediatric maintenance infusion planning for patients in the 10–20 kg range.
  • Adult or larger-patient maintenance rate checks for weights above 20 kg.
  • Cross-checking an hourly fluid estimate against the 100/50/20 daily method.

Examples

1. Adult 70 kg maintenance rate

Clinician

Background

A clinician needs a quick maintenance fluid estimate for a 70 kg adult.

Problem

The hourly rate must account for the first 10 kg, the next 10 kg, and the remaining weight above 20 kg.

How to use

Enter 70 as the weight, select kg, and leave Decimal Places at 1.

{"weight":70,"weightUnit":"kg","decimalPlaces":1}

Outcome

The calculator returns 110 mL/h and 2640 mL/day using the 4-2-1 rule, with a 2500 mL/day 100/50/20 cross-check.

2. Pediatric 12 kg maintenance rate

Pediatric care team

Background

A pediatric patient weighs 12 kg and requires an initial maintenance fluid estimate.

Problem

The team wants to calculate the rate for a weight in the 10–20 kg range.

How to use

Enter 12 as the weight, select kg, and review the calculated hourly and daily values.

{"weight":12,"weightUnit":"kg","decimalPlaces":1}

FAQ

What is the 4-2-1 rule?

It estimates hourly maintenance fluid: 4 mL/kg/h for the first 10 kg, 2 mL/kg/h for the next 10 kg, and 1 mL/kg/h for each kilogram above 20 kg.

Can I enter weight in pounds?

Yes. Select lb as the weight unit, and the calculator converts the value to kilograms before calculating.

What does the calculator output?

It provides the maintenance rate in mL/h, the estimated 24-hour volume, the patient category, and a 100/50/20 mL/kg/day comparison.

Is this calculator suitable for every patient?

No. The 4-2-1 rule is an initial estimate and may require adjustment for clinical conditions such as fever, burns, fluid losses, SIADH, or heart and kidney dysfunction.

Is this medical advice?

No. Use the result as a calculation reference and rely on a qualified healthcare professional for patient-specific decisions.

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Outcome

The calculator returns 44 mL/h and 1056 mL/day using the 4-2-1 rule, with a 1100 mL/day 100/50/20 cross-check.

3. Weight entered in pounds

Healthcare learner

Background

A learner has a patient's weight in pounds but needs a 4-2-1 maintenance rate.

Problem

The calculation requires kilograms, while the available weight uses a different unit.

How to use

Enter the weight and select lb; the calculator converts it to kilograms before applying the rule.

Outcome

The result shows the converted kilogram weight along with the hourly maintenance rate, 24-hour total, and daily-method cross-check.