Calculate the hourly maintenance fluid rate using the Holliday-Segar 4-2-1 rule: first 10 kg at 4 mL/kg/h, next 10 kg at 2 mL/kg/h, each kg above 20 at 1 mL/kg/h. Also shows the 24-hour total and the 100/50/20 mL/kg/day daily method for cross-checking. Weight in kg or lb (auto-converted). Derived from Holliday-Segar Pediatrics 1957, MDCalc, and Meyers 2009. Not medical advice.
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Key facts
Category
Health
Input types
number, select
Output type
json
Sample coverage
4
API ready
Yes
Overview
Calculate an hourly maintenance fluid rate with the Holliday-Segar 4-2-1 rule. Enter weight in kilograms or pounds to see the rate in mL/h, the estimated 24-hour total, and a 100/50/20 mL/kg/day cross-check. This calculator is an estimate, not medical advice.
When to use
Estimate maintenance fluid requirements for a patient who is fasting or unable to take fluids orally.
Check a pediatric or adult maintenance infusion rate using the 4-2-1 rule.
Compare the hourly 4-2-1 estimate with the 100/50/20 mL/kg/day method.
How it works
1Enter the patient's body weight.
2Select kg or lb; weight entered in pounds is converted to kilograms.
3The calculator applies 4 mL/kg/h for the first 10 kg, 2 mL/kg/h for the next 10 kg, and 1 mL/kg/h above 20 kg.
4Review the hourly rate, 24-hour total, patient category, and daily-method cross-check in the JSON result.
Use cases
Pediatric maintenance infusion planning for patients in the 10–20 kg range.
Adult or larger-patient maintenance rate checks for weights above 20 kg.
Cross-checking an hourly fluid estimate against the 100/50/20 daily method.
Examples
1. Adult 70 kg maintenance rate
Clinician
Background
A clinician needs a quick maintenance fluid estimate for a 70 kg adult.
Problem
The hourly rate must account for the first 10 kg, the next 10 kg, and the remaining weight above 20 kg.
How to use
Enter 70 as the weight, select kg, and leave Decimal Places at 1.
{"weight":70,"weightUnit":"kg","decimalPlaces":1}
Outcome
The calculator returns 110 mL/h and 2640 mL/day using the 4-2-1 rule, with a 2500 mL/day 100/50/20 cross-check.
2. Pediatric 12 kg maintenance rate
Pediatric care team
Background
A pediatric patient weighs 12 kg and requires an initial maintenance fluid estimate.
Problem
The team wants to calculate the rate for a weight in the 10–20 kg range.
How to use
Enter 12 as the weight, select kg, and review the calculated hourly and daily values.
{"weight":12,"weightUnit":"kg","decimalPlaces":1}
FAQ
What is the 4-2-1 rule?
It estimates hourly maintenance fluid: 4 mL/kg/h for the first 10 kg, 2 mL/kg/h for the next 10 kg, and 1 mL/kg/h for each kilogram above 20 kg.
Can I enter weight in pounds?
Yes. Select lb as the weight unit, and the calculator converts the value to kilograms before calculating.
What does the calculator output?
It provides the maintenance rate in mL/h, the estimated 24-hour volume, the patient category, and a 100/50/20 mL/kg/day comparison.
Is this calculator suitable for every patient?
No. The 4-2-1 rule is an initial estimate and may require adjustment for clinical conditions such as fever, burns, fluid losses, SIADH, or heart and kidney dysfunction.
Is this medical advice?
No. Use the result as a calculation reference and rely on a qualified healthcare professional for patient-specific decisions.