What does this calculator estimate?

It estimates single-pool Kt/V (spKt/V) for an intermittent hemodialysis session.

Which formula does it use?

It uses the Daugirdas second-generation formula: −ln(R − 0.008·t) + (4 − 3.5·R)·UF/W.

What inputs are required?

Pre- and post-dialysis BUN, treatment time, ultrafiltration volume, and post-dialysis weight are required.

How should post-dialysis BUN be collected?

Use a slow-flow or stop-pump collection technique, as specified in the tool description.

Does this calculator apply to peritoneal dialysis or CRRT?

No. It is intended for intermittent hemodialysis and not for peritoneal dialysis, CRRT, or SLED.

Elysia Tools

Navigation

Health

Dialysis Dose Kt/V Calculator (Daugirdas 2nd Gen.)

Estimate single-pool Kt/V (spKt/V) for a hemodialysis session with the Daugirdas second-generation formula: Kt/V = −ln(R − 0.008·t) + (4 − 3.5·R) × UF / W, where R = Post-BUN/Pre-BUN, t = treatment time (h), UF = ultrafiltration volume (kg), W = post-dialysis weight (kg). The first term captures urea removal and generation; the second corrects for volume contraction. KDOQI target: spKt/V ≥1.2 per session (minimum delivered dose) for conventional thrice-weekly hemodialysis, target ~1.4. Requires post-dialysis BUN drawn by slow-flow/stop-pump technique. Derived from Daugirdas JT, J Am Soc Nephrol 1993. Valid for intermittent hemodialysis; not for peritoneal dialysis or CRRT/SLED. Not medical advice.

Execution

Run this tool

Fill in the form, run the tool, and review the result in one place.

Prepared example runs

Click an example to fill the form automatically. File inputs still need an upload.

2 examples

Pre 90, Post 30, t=4h, UF=2kg, W=70kg → Kt/V = 1.2805 (minimum met)

R = 30/90 = 0.3333. Kt/V = −ln(0.3333 − 0.008×4) + (4 − 3.5×0.3333)×2/70 = 1.2805. Meets KDOQI minimum (≥1.2).

{"result":"Kt/V = 1.2805 (Minimum met 1.2–1.4). Method: Daugirdas 2nd-gen, Kt/V = −ln(R − 0.008·t) + (4 − 3.5·R)·UF/W.","metadata":{"input":{"preBun":90,"postBun":30,"treatmentTime":4,"ultrafiltration":2,"postWeight":70},"result":{"ktv":1.2805,"ratioR":0.3333,"status":"Minimum met (1.2–1.4)","note":"Meets KDOQI minimum delivered dose (≥1.2). Consider escalating toward 1.4.","method":"Daugirdas 2nd-gen: Kt/V = −ln(R − 0.008·t) + (4 − 3.5·R)·UF/W","model":"Daugirdas JT. J Am Soc Nephrol 1993;4(5):1205-1213. Single-pool. Not medical advice."}}}

Pre 100, Post 35, t=3.5h, UF=3kg, W=80kg → Kt/V = 1.2373 (minimum met)

R = 35/100 = 0.35. Kt/V = −ln(0.35 − 0.008×3.5) + (4 − 3.5×0.35)×3/80 = 1.2373. Higher UF contribution with shorter session.

{"result":"Kt/V = 1.2373 (Minimum met 1.2–1.4). Method: Daugirdas 2nd-gen, Kt/V = −ln(R − 0.008·t) + (4 − 3.5·R)·UF/W.","metadata":{"input":{"preBun":100,"postBun":35,"treatmentTime":3.5,"ultrafiltration":3,"postWeight":80},"result":{"ktv":1.2373,"ratioR":0.35,"status":"Minimum met (1.2–1.4)","note":"Meets KDOQI minimum delivered dose (≥1.2). Consider escalating toward 1.4.","method":"Daugirdas 2nd-gen: Kt/V = −ln(R − 0.008·t) + (4 − 3.5·R)·UF/W","model":"Daugirdas JT. J Am Soc Nephrol 1993;4(5):1205-1213. Single-pool. Not medical advice."}}}

Inputs

Set the required fields, then run the tool.

6 options

SettingsAdjust formats, ranges, numbers, and modes.6

Pre-dialysis BUN (mg/dL)numberRequiredPre-dialysis blood urea nitrogen in mg/dL. Must be positive.Post-dialysis BUN (mg/dL)numberRequiredPost-dialysis blood urea nitrogen in mg/dL (slow-flow technique). Must be positive and less than pre-BUN.Treatment time (hours)numberRequiredDialysis treatment time in hours. Must be positive.Ultrafiltration volume UF (kg)numberRequiredIntradialytic weight loss (ultrafiltration volume) in kg. Must be ≥0.Post-dialysis weight W (kg)numberRequiredPost-dialysis body weight in kg. Must be positive.Decimal PlacesnumberOptional

Result

Ready for a run

Run the tool to preview files, text, structured data, or streamed output here.

Samples

Dialysis Dose Kt/V Calculator (Daugirdas 2nd Gen.)

Run this tool

Prepared example runs

Inputs

Result

Examples that match this tool

Continue with connected tools and hubs

Prepared example runs

Inputs

Result

Learn when to use this tool, what it supports, and how real users apply it.

Key facts

Overview

When to use

How it works

Use cases

Examples

1. Four-hour session reaching the minimum reference

2. Shorter session with higher ultrafiltration

FAQ

Web Image Processing Python Samples

Duplicate Line Samples

Special Characters Samples

Code Comment Samples

eGFR Calculator (CKD-EPI 2021 Race-Free)

eGFR Calculator (MDRD Simplified)

2048 Game

Audio Declicker

Kidney Function, Dialysis, and Renal Dose Calculators

Audio Encoding and Format Conversion Tools

Image Format Conversion and Animated Export Tools

JSON Interchange and Format Translation Tools