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eGFR Calculator (CKD-EPI 2021 Race-Free)

· Last updated：2026-08-05

This tool is for informational purposes only and does not constitute medical, financial, or legal advice; consult a qualified professional for advice.

Estimate glomerular filtration rate (eGFR) with the CKD-EPI 2021 race-free creatinine equation: eGFR = 142 × min(SCr/κ, 1)^α × max(SCr/κ, 1)^(−1.200) × 0.9938^Age × 1.012 if female, where κ = 0.7 (female) / 0.9 (male) and α = −0.241 (female) / −0.302 (male). This 2021 update (Inker et al., NEJM 2021) removed the race multiplier from the 2009 equation and changed the leading coefficient from 141 to 142. Returns a BSA-INDEXED eGFR for CKD staging (G1–G5); for drug dosing use un-indexed CrCl (Cockcroft-Gault). Valid for stable adults, not AKI/pregnancy/amputees/extremes. Not medical advice.

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Tool usage guide

Learn when to use this tool, what it supports, and how real users apply it.

Key facts

Category
Health
Input types
number, select
Output type
json
Sample coverage
4
API ready
Yes

Overview

The eGFR Calculator estimates glomerular filtration rate for stable adults using the CKD-EPI 2021 race-free creatinine equation. Enter age, sex, and serum creatinine in mg/dL to receive a BSA-indexed eGFR in mL/min/1.73 m² and an associated CKD stage. This tool is not medical advice.

When to use

  • Estimate kidney filtration for CKD staging in a stable adult.
  • Review how age, sex, and serum creatinine affect an eGFR result.
  • Apply the CKD-EPI 2021 race-free equation consistently in clinical or educational calculations.

How it works

  1. 1Enter an age from 18 to 120 years, select male or female, and provide a positive serum creatinine value in mg/dL.
  2. 2The calculator applies the CKD-EPI 2021 race-free creatinine equation, using sex-specific κ and α values.
  3. 3It returns eGFR in mL/min/1.73 m² and assigns a CKD stage from G1 to G5.
  4. 4Choose the number of decimal places for the displayed result; the default is 4.

Use cases

  • Estimate and document eGFR for chronic kidney disease staging.
  • Teach the effect of age, sex, and serum creatinine on the CKD-EPI 2021 calculation.
  • Standardize repeat eGFR calculations for stable adult patients during clinical review.

Examples

1. eGFR estimate for a 60-year-old man

Clinician or medical student

Background

A stable 60-year-old male patient has a serum creatinine of 1.4 mg/dL.

Problem

Estimate kidney filtration and identify the corresponding CKD stage.

How to use

Enter age 60, select Male, enter serum creatinine 1.4 mg/dL, and set decimal places to 4.

{"age":60,"sex":"male","serumCreatinine":1.4,"decimalPlaces":4}

Outcome

The calculator returns an eGFR of 57.5394 mL/min/1.73 m² and CKD stage G3a, described as mildly to moderately decreased.

2. eGFR estimate for a 40-year-old woman

Healthcare learner

Background

A stable 40-year-old female patient has a serum creatinine of 0.7 mg/dL.

Problem

Calculate eGFR at the female CKD-EPI equation's κ knot point.

How to use

Enter age 40, select Female, enter serum creatinine 0.7 mg/dL, and use 4 decimal places.

FAQ

What equation does this calculator use?

It uses the CKD-EPI 2021 race-free creatinine equation described by Inker and colleagues.

What units should I enter for serum creatinine?

Enter serum creatinine in mg/dL.

What does the eGFR result represent?

It is a body-surface-area-indexed estimate reported in mL/min/1.73 m² for CKD staging.

Can I use this result for drug dosing?

No. The result is BSA-indexed; drug dosing should use an appropriate un-indexed creatinine clearance method, such as Cockcroft-Gault.

When should this calculator not be relied on?

It is intended for stable adults and is not validated here for AKI, pregnancy, amputees, or body-size extremes.

Hub

Renal Function, Dialysis, and Dose-Model Checks

Compare kidney-function formulas, dialysis adequacy metrics, and renal medication math in an educational workflow that avoids patient-specific dosing or diagnosis.

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eGFR Calculator (MDRD Simplified)

Estimate glomerular filtration rate (eGFR) with the simplified 4-variable MDRD equation (2006 re-expressed, IDMS-traceable): eGFR (mL/min/1.73 m²) = 175 × SCr^−1.154 × Age^−0.203 × (0.742 if female) × (1.212 if Black). The 175 constant replaced the original 186 after IDMS-standardized creatinine calibration. The legacy race coefficient 1.212 is OFF by default (the 2021 CKD-EPI race-free equation removed it) and is provided only for historical comparison. Returns a BSA-INDEXED eGFR for CKD staging (G1–G5); for drug dosing use un-indexed CrCl (Cockcroft-Gault). Derived from Levey AS et al., Ann Intern Med 2006. Valid for stable adults, not AKI/pregnancy/extremes. Not medical advice.

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{"age":40,"sex":"female","serumCreatinine":0.7,"decimalPlaces":4}

Outcome

The calculator returns an eGFR of 112.0543 mL/min/1.73 m² and CKD stage G1, indicating normal or high eGFR when interpreted with kidney-damage markers.