What does this calculator estimate?

It estimates eGFR with the simplified 4-variable MDRD equation and reports a BSA-indexed result in mL/min/1.73 m².

What inputs are required?

Age and serum creatinine are required. Sex is available as a male or female selection and defaults to Male.

Is the race coefficient enabled by default?

No. The 1.212 coefficient is off by default and is provided only for historical comparison.

Can I use this result for medication dosing?

No. This is a BSA-indexed eGFR for CKD staging; drug dosing generally requires an un-indexed creatinine clearance estimate such as Cockcroft-Gault.

When should this MDRD calculator not be used?

It is not intended for acute kidney injury, pregnancy, or body-size extremes, and it is not a substitute for medical advice.

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eGFR Calculator (MDRD Simplified)

Estimate glomerular filtration rate (eGFR) with the simplified 4-variable MDRD equation (2006 re-expressed, IDMS-traceable): eGFR (mL/min/1.73 m²) = 175 × SCr^−1.154 × Age^−0.203 × (0.742 if female) × (1.212 if Black). The 175 constant replaced the original 186 after IDMS-standardized creatinine calibration. The legacy race coefficient 1.212 is OFF by default (the 2021 CKD-EPI race-free equation removed it) and is provided only for historical comparison. Returns a BSA-INDEXED eGFR for CKD staging (G1–G5); for drug dosing use un-indexed CrCl (Cockcroft-Gault). Derived from Levey AS et al., Ann Intern Med 2006. Valid for stable adults, not AKI/pregnancy/extremes. Not medical advice.

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2 examples

Male, 60 y, SCr 1.4 → eGFR = 51.6942 mL/min/1.73m² (G3a)

eGFR = 175 × 1.4^−1.154 × 60^−0.203 = 51.6942 mL/min/1.73 m². Stage G3a (mildly to moderately decreased).

{"result":"eGFR = 51.6942 mL/min/1.73 m² (CKD stage G3a — mildly to moderately decreased). Method: simplified MDRD, eGFR = 175·SCr^−1.154·age^−0.203 × 0.742 if female.","metadata":{"input":{"age":60,"sex":"male","serumCreatinine":1.4,"raceCoefficient":false},"result":{"egfr":51.6942,"unit":"mL/min/1.73 m²","ckdStage":"G3a","ckdDescription":"Mildly to moderately decreased","raceCoefficientApplied":false,"method":"Simplified MDRD: eGFR = 175·SCr^−1.154·age^−0.203 × 0.742 if female × 1.212 if Black","model":"Levey AS et al. Ann Intern Med 2006 (IDMS-traceable, constant 175). BSA-indexed. Not medical advice."}}}

Female, 50 y, SCr 1.6, race coefficient ON → eGFR = 41.3523 mL/min/1.73m² (G3b)

Without race coefficient: 175 × 1.6^−1.154 × 50^−0.203 × 0.742 = 34.1190. With 1.212: × 1.212 = 41.3523 mL/min/1.73 m². Demonstrates the legacy coefficient.

{"result":"eGFR = 41.3523 mL/min/1.73 m² (CKD stage G3b — moderately to severely decreased). Method: simplified MDRD, eGFR = 175·SCr^−1.154·age^−0.203 × 0.742 if female × 1.212 (legacy race coefficient).","metadata":{"input":{"age":50,"sex":"female","serumCreatinine":1.6,"raceCoefficient":true},"result":{"egfr":41.3523,"unit":"mL/min/1.73 m²","ckdStage":"G3b","ckdDescription":"Moderately to severely decreased","raceCoefficientApplied":true,"method":"Simplified MDRD: eGFR = 175·SCr^−1.154·age^−0.203 × 0.742 if female × 1.212 if Black","model":"Levey AS et al. Ann Intern Med 2006 (IDMS-traceable, constant 175). BSA-indexed. Not medical advice."}}}

Inputs

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5 options

SettingsAdjust formats, ranges, numbers, and modes.4

Age (years)numberRequiredPatient age in years. Must be ≥18 and ≤120.SexselectOptionalSerum Creatinine (mg/dL)numberRequiredSerum creatinine in mg/dL (IDMS-traceable). Must be positive.Decimal PlacesnumberOptional

TogglesEnable or disable optional behavior.1

Apply race coefficient 1.212 (legacy MDRD)checkboxOptionalEnabled when checkedIf checked, multiplies by 1.212 (legacy Black coefficient). OFF by default — modern NKF/ASN guidance uses race-free CKD-EPI 2021.

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eGFR Calculator (MDRD Simplified)

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Examples

1. Standard MDRD estimate for a 60-year-old man

2. Historical coefficient comparison for a female patient

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