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eGFR Calculator (MDRD Simplified)

· Last updated：2026-08-05

This tool is for informational purposes only and does not constitute medical, financial, or legal advice; consult a qualified professional for advice.

Estimate glomerular filtration rate (eGFR) with the simplified 4-variable MDRD equation (2006 re-expressed, IDMS-traceable): eGFR (mL/min/1.73 m²) = 175 × SCr^−1.154 × Age^−0.203 × (0.742 if female) × (1.212 if Black). The 175 constant replaced the original 186 after IDMS-standardized creatinine calibration. The legacy race coefficient 1.212 is OFF by default (the 2021 CKD-EPI race-free equation removed it) and is provided only for historical comparison. Returns a BSA-INDEXED eGFR for CKD staging (G1–G5); for drug dosing use un-indexed CrCl (Cockcroft-Gault). Derived from Levey AS et al., Ann Intern Med 2006. Valid for stable adults, not AKI/pregnancy/extremes. Not medical advice.

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Written by the Elysia Tools team

Tool usage guide

Learn when to use this tool, what it supports, and how real users apply it.

Key facts

Category
Health
Input types
number, select, checkbox
Output type
json
Sample coverage
4
API ready
Yes

Overview

Estimate glomerular filtration rate with the simplified 4-variable MDRD equation using age, sex, and IDMS-traceable serum creatinine. The calculator returns a BSA-indexed eGFR in mL/min/1.73 m² and assigns a CKD stage from G1 to G5 for stable adults.

When to use

  • Estimate eGFR for CKD staging in a stable adult.
  • Review how age, sex, and serum creatinine affect an MDRD eGFR result.
  • Compare a standard race-free MDRD estimate with the legacy 1.212 coefficient for historical reference.

How it works

  1. 1Enter an age from 18 to 120 years and a positive serum creatinine value in mg/dL.
  2. 2Select the patient's sex; the female adjustment is applied when Female is selected.
  3. 3The calculator applies the simplified MDRD formula: 175 × SCr^−1.154 × age^−0.203, with the female factor when applicable.
  4. 4Review the eGFR, unit, CKD stage, and whether the legacy race coefficient was applied.

Use cases

  • Clinicians and students reviewing eGFR calculations and CKD stage thresholds.
  • Patients organizing stable kidney-function results for discussion with a healthcare professional.
  • Researchers or analysts comparing standard MDRD outputs with the legacy coefficient for historical data.

Examples

1. Standard MDRD estimate for a 60-year-old man

Clinician or medical student

Background

A stable 60-year-old male has an IDMS-traceable serum creatinine of 1.4 mg/dL.

Problem

Estimate eGFR and identify the corresponding CKD stage.

How to use

Enter age 60, select Male, enter serum creatinine 1.4 mg/dL, leave the race coefficient off, and set 4 decimal places.

{"age":60,"sex":"male","serumCreatinine":1.4,"raceCoefficient":false,"decimalPlaces":4}

Outcome

The calculator returns an eGFR of 51.6942 mL/min/1.73 m² and CKD stage G3a, described as mildly to moderately decreased.

2. Historical coefficient comparison for a female patient

Renal data reviewer

Background

A 50-year-old female has a serum creatinine of 1.6 mg/dL, and an analyst needs to reproduce a historical MDRD calculation.

Problem

Show the MDRD result when the legacy 1.212 coefficient is applied.

How to use

Enter age 50, select Female, enter serum creatinine 1.6 mg/dL, enable the legacy race coefficient, and set 4 decimal places.

FAQ

What does this calculator estimate?

It estimates eGFR with the simplified 4-variable MDRD equation and reports a BSA-indexed result in mL/min/1.73 m².

What inputs are required?

Age and serum creatinine are required. Sex is available as a male or female selection and defaults to Male.

Is the race coefficient enabled by default?

No. The 1.212 coefficient is off by default and is provided only for historical comparison.

Can I use this result for medication dosing?

No. This is a BSA-indexed eGFR for CKD staging; drug dosing generally requires an un-indexed creatinine clearance estimate such as Cockcroft-Gault.

When should this MDRD calculator not be used?

It is not intended for acute kidney injury, pregnancy, or body-size extremes, and it is not a substitute for medical advice.

Hub

Renal Function, Dialysis, and Dose-Model Checks

Compare kidney-function formulas, dialysis adequacy metrics, and renal medication math in an educational workflow that avoids patient-specific dosing or diagnosis.

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{"age":50,"sex":"female","serumCreatinine":1.6,"raceCoefficient":true,"decimalPlaces":4}

Outcome

The calculator returns an eGFR of 41.3523 mL/min/1.73 m² and CKD stage G3b. The coefficient is labeled as a legacy option for historical comparison.