Education
Compute AD offspring risk (Aa×aa 1:1, Aa×Aa 3:1, AA×any all affected), chi-square fit of observed children, and hallmark checks including male-to-male transmission that rules out X-linked dominant. Derived from Griffiths, Hartl & Clark 2007, StatPearls, OMIM. Educational use only.
autosomal-dominant-pedigreeEducation
Compute per-child and cumulative autosomal recessive disease risk from parental statuses (carrier / affected / non-carrier / unknown via population carrier rate), including the 2/3 carrier rule. Derived from Griffiths, Hartl & Clark 2007, StatPearls. Educational use only.
autosomal-recessive-riskFinance
Convert odds between decimal, fractional, and American formats with implied probability, plus parlay combination odds and no-vig fair-odds calculation.
betting-odds-calculatorEducation
Expected heterozygosity loss through a population bottleneck: H_final = H₀(1−1/2Nb)^t(1−1/2Nr)^g, retention, inbreeding F, harmonic-mean Ne, and one-generation allele survival. Derived from Wright 1931, Nei et al. 1975, Hartl & Clark 2007, StatPearls. Educational use only.
bottleneck-effect-simulatorHealth
Convert serum bilirubin (total/direct/indirect) between mg/dL and µmol/L. Factor 17.1 (molar mass 584.67 g/mol). Derived from Young 1987, StatPearls, AAP 2004, Bhutani. Not medical advice.
bilirubin-unit-converterMedia
Create an artificial-double-tracking style doubled vocal with micro-delay, pitch drift, and stereo widening.
audio-vocal-doublerHealth
Solve any one of pH/HCO₃⁻/PaCO₂ from the other two via pH = 6.1 + log10(HCO₃⁻/(0.03×PaCO₂)). Reports linear Henderson [H⁺] cross-check. Derived from Henderson 1908, Hasselbalch 1916, Siggaard-Andersen 1974, LITFL, StatPearls, Berend 2016. Not medical advice.
bicarbonate-ph-conversionHealth
Calculate base excess (BE) using the Siggaard-Andersen formula. BE < −3 metabolic acidosis, > +3 metabolic alkalosis. HCO₃⁻ auto-calculated from pH + PaCO₂ if omitted. Derived from Siggaard-Andersen 1974, Cornell PICU, Medscape, and Langer 2022. Not medical advice.
base-excess-calculatorHealth
Complete ABG analysis: pH, primary disorder, compensation (Winter's formula), anion gap ± albumin correction, delta ratio for mixed disorder detection. Derived from Emmett 2016, Kraut 2007, Rastegar 2007, LITFL, MDCalc, and Adrogué 1998. Not medical advice.
blood-gas-anion-gapHealth
Calculate the absolute bioavailability F of an extravascular (typically oral) dose: F = (AUC_po · Dose_iv) / (AUC_iv · Dose_po), where AUC_po and AUC_iv are the areas under the concentration-time curve after oral and IV dosing, and the doses correct for any difference in amount administered. F is dimensionless and lies in [0, 1]; IV bioavailability is by definition 1, while oral F < 1 reflects incomplete absorption and/or first-pass metabolism. AUC can be in any consistent unit (e.g. mg·h/L) since it cancels out of the ratio. Valid only for linear pharmacokinetics, the same drug molecule, and doses within the linear range. Not medical advice.
bioavailability-calculatorMedia
Separate a music mix into drums, bass, other, vocals, guitar, and piano, then download one ZIP.
audio-stem-separation-proMedia
Measure and adjust vocal level relative to an instrumental bed, with a transparent loudness report.
audio-vocal-instrumental-balance