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Absolute Neutrophil Count (ANC) Calculator Calculate the Absolute Neutrophil Count (ANC) = WBC × (segmented % + band %) / 100. Unit selectable: cells/µL or ×10⁹/L (1 ×10⁹/L = 1000 cells/µL). Adult reference ≥ 1500 cells/µL. Neutropenia risk strata: mild 1000–1500, moderate 500–1000, severe < 500 (agranulocytosis < 200) — high risk of serious infection, and febrile neutropenia is a medical emergency. Clinical uses: chemotherapy cycles typically require ANC ≥ 1500 to proceed and ≥ 500 for discharge from protective isolation; carbimazole/clozapine monitoring; congenital neutropenia workup. Neutrophilia > 7500 suggests bacterial infection, inflammation, steroids, or a myeloproliferative neoplasm. If only segmented % is reported, set band % to 0; if the instrument reports an absolute neutrophil count directly (NE#), this tool is not needed. Based on ASCO/IDSA neutropenia guidance, Boxer ASH 2012, and MDCalc. Not medical advice.