Health
Vancomycin Empiric Dosing Calculator (2020 ASHP/IDSA)
Empiric starting dosing for vancomycin per the 2020 ASHP/IDSA/PIDS/SIDP consensus guideline. Loading dose: 20–25 mg/kg actual body weight (obesity cap 3000 mg). Maintenance dose: 15–20 mg/kg actual body weight every 8–12 h. Optional creatinine clearance (CrCl) input suggests an empiric dosing interval (≥90 → q8h, 50–89 → q12h, 30–49 → q18–24h, 10–29 → q24h, <10 → q24–48h). Optional measured trough is classified against the SECONDARY trough target of 15–20 mg/L. The 2020 guideline shifted the primary monitoring target to AUC₀₋₂₄/MIC = 400–600 mg·h/L (within first 24–48 h); trough-only monitoring is no longer recommended as primary. Derived from Rybak MJ et al., Am J Health-Syst Pharm 2020. Empiric start doses ONLY — individualize by AUC-guided Bayesian monitoring. Not medical advice.
Quick start
Call this tool from your code in three languages.
curl -X POST 'https://api.elysiatools.com/en/api/tools/vancomycin-dosing' \
-H 'Content-Type: application/json' \
-d '{"weight":75,"crcl":80,"trough":0,"decimalPlaces":4}'API reference
Send a POST request with your inputs as JSON. File parameters require a separate upload first.
Endpoint
POST https://api.elysiatools.com/en/api/tools/vancomycin-dosingParameters
| Name | Type | Required | Description |
|---|---|---|---|
| weight | number | Yes | Actual body weight in kg. Must be positive. |
| crcl | number | No | Optional CrCl in mL/min. Guides empiric dosing interval. Must be ≥0. |
| trough | number | No | Optional measured/target trough in mg/L for classification against the secondary trough target. |
| decimalPlaces | number | No | — |
Response format
JSON result
{
"key": {...},
"metadata": {
"key": "value"
},
"error": "Error message (optional)",
"message": "Notification message (optional)"
}MCP integration
Add this tool to your Model Context Protocol server so AI agents can list and call it.
Server configuration
Add this block to your MCP client configuration:
{
"mcpServers": {
"elysiatools-vancomycin-dosing": {
"name": "vancomycin-dosing",
"description": "Empiric starting dosing for vancomycin per the 2020 ASHP/IDSA/PIDS/SIDP consensus guideline. Loading dose: 20–25 mg/kg actual body weight (obesity cap 3000 mg). Maintenance dose: 15–20 mg/kg actual body weight every 8–12 h. Optional creatinine clearance (CrCl) input suggests an empiric dosing interval (≥90 → q8h, 50–89 → q12h, 30–49 → q18–24h, 10–29 → q24h, <10 → q24–48h). Optional measured trough is classified against the SECONDARY trough target of 15–20 mg/L. The 2020 guideline shifted the primary monitoring target to AUC₀₋₂₄/MIC = 400–600 mg·h/L (within first 24–48 h); trough-only monitoring is no longer recommended as primary. Derived from Rybak MJ et al., Am J Health-Syst Pharm 2020. Empiric start doses ONLY — individualize by AUC-guided Bayesian monitoring. Not medical advice.",
"baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=vancomycin-dosing",
"command": "",
"args": [],
"env": {},
"isActive": true,
"type": "sse"
}
}
}List available tools
After connecting to the SSE endpoint, list the exposed tools:
{
"jsonrpc": "2.0",
"id": 1,
"method": "tools/list"
}Call this tool
Invoke the tool by its id, passing arguments built from its parameters:
{
"jsonrpc": "2.0",
"id": 2,
"method": "tools/call",
"params": {
"name": "vancomycin-dosing",
"arguments": {
"weight": 75,
"crcl": 80,
"trough": 0,
"decimalPlaces": 4
}
}
}