Health
Drug Clearance Calculator (CL)
Calculate drug clearance CL in two modes. (A) Definition: CL = elimination rate / concentration, valid for any pharmacokinetic model. (B) Linear first-order: CL = k · Vd (or derive k from t½ via k = ln2 / t½). Also reports the relationship t½ = 0.693 · Vd / CL. CL is a definitional parameter independent of Vd. Linear mode applies only to first-order elimination — NOT to Michaelis-Menten drugs (phenytoin, high-dose ethanol). Reference: theophylline CL ≈ 2.8 L/h in a 70 kg non-smoking adult. Not medical advice.
Quick start
Call this tool from your code in three languages.
curl -X POST 'https://api.elysiatools.com/en/api/tools/drug-clearance-calculator' \
-H 'Content-Type: application/json' \
-d '{"mode":"definition","eliminationRate":14,"concentration":5,"k":0,"halfLife":0,"vd":0,"decimalPlaces":4}'API reference
Send a POST request with your inputs as JSON. File parameters require a separate upload first.
Endpoint
POST https://api.elysiatools.com/en/api/tools/drug-clearance-calculatorParameters
| Name | Type | Required | Description |
|---|---|---|---|
| mode | select | No | — |
| eliminationRate | number | No | Mass eliminated per unit time. Required in Definition mode. |
| concentration | number | No | Blood/plasma concentration. Required in Definition mode. |
| k | number | No | First-order elimination rate constant. Linear mode: provide k OR t½. |
| halfLife | number | No |
MCP integration
Add this tool to your Model Context Protocol server so AI agents can list and call it.
Server configuration
Add this block to your MCP client configuration:
{
"mcpServers": {
"elysiatools-drug-clearance-calculator": {
"name": "drug-clearance-calculator",
"description": "Calculate drug clearance CL in two modes. (A) Definition: CL = elimination rate / concentration, valid for any pharmacokinetic model. (B) Linear first-order: CL = k · Vd (or derive k from t½ via k = ln2 / t½). Also reports the relationship t½ = 0.693 · Vd / CL. CL is a definitional parameter independent of Vd. Linear mode applies only to first-order elimination — NOT to Michaelis-Menten drugs (phenytoin, high-dose ethanol). Reference: theophylline CL ≈ 2.8 L/h in a 70 kg non-smoking adult. Not medical advice.",
"baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=drug-clearance-calculator",
"command": "",
"args": [],
"env": {},
"isActive": true,
"type": "sse"
}
}
}List available tools
After connecting to the SSE endpoint, list the exposed tools:
{
"jsonrpc": "2.0",
"id": 1,
"method": "tools/list"
}Call this tool
Invoke the tool by its id, passing arguments built from its parameters:
{
"jsonrpc": "2.0",
"id": 2,
"method": "tools/call",
"params": {
"name": "drug-clearance-calculator",
"arguments": {
"mode": "definition",
"eliminationRate": 14,
"concentration": 5,
"k": 0,
"halfLife": 0,
"vd": 0,
"decimalPlaces": 4
}
}
}