Health

Henderson-Hasselbalch Equation (pH / HCO₃⁻ / PCO₂)

Solve any one of pH/HCO₃⁻/PaCO₂ from the other two via pH = 6.1 + log10(HCO₃⁻/(0.03×PaCO₂)). Reports linear Henderson [H⁺] cross-check. Derived from Henderson 1908, Hasselbalch 1916, Siggaard-Andersen 1974, LITFL, StatPearls, Berend 2016. Not medical advice.

json· JSON resultOpen tool

Quick start

Call this tool from your code in three languages.

cURL

curl -X POST 'https://api.elysiatools.com/en/api/tools/bicarbonate-ph-conversion' \
  -H 'Content-Type: application/json' \
  -d '{"ph":0,"hco3":24,"paco2":40,"decimalPlaces":2}'

API reference

Send a POST request with your inputs as JSON. File parameters require a separate upload first.

Endpoint

HTTP

POST https://api.elysiatools.com/en/api/tools/bicarbonate-ph-conversion

Parameters

Name	Type	Required	Description
ph	number	No	Arterial pH. Provide any TWO of pH / HCO₃⁻ / PaCO₂; the tool solves the third. If all three are provided, the tool checks Henderson-Hasselbalch consistency instead.
hco3	number	No	Bicarbonate (mmol/L). Provide any TWO of pH / HCO₃⁻ / PaCO₂.
paco2	number	No	Arterial PaCO₂ (mmHg). Provide any TWO of pH / HCO₃⁻ / PaCO₂.
decimalPlaces	number	No	—

Response format

JSON result

MCP integration

Add this tool to your Model Context Protocol server so AI agents can list and call it.

Server configuration

Add this block to your MCP client configuration:

mcp.json

{
  "mcpServers": {
    "elysiatools-bicarbonate-ph-conversion": {
      "name": "bicarbonate-ph-conversion",
      "description": "Solve any one of pH/HCO₃⁻/PaCO₂ from the other two via pH = 6.1 + log10(HCO₃⁻/(0.03×PaCO₂)). Reports linear Henderson [H⁺] cross-check. Derived from Henderson 1908, Hasselbalch 1916, Siggaard-Andersen 1974, LITFL, StatPearls, Berend 2016. Not medical advice.",
      "baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=bicarbonate-ph-conversion",
      "command": "",
      "args": [],
      "env": {},
      "isActive": true,
      "type": "sse"
    }
  }
}

List available tools

After connecting to the SSE endpoint, list the exposed tools:

tools/list

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/list"
}

Call this tool

Invoke the tool by its id, passing arguments built from its parameters:

tools/call

{
  "jsonrpc": "2.0",
  "id": 2,
  "method": "tools/call",
  "params": {
    "name": "bicarbonate-ph-conversion",
    "arguments": {
  "ph": 0,
  "hco3": 24,
  "paco2": 40,
  "decimalPlaces": 2
}
  }
}

Chain multiple tools in one session with a comma-separated toolId list, e.g. /mcp/sse?toolId=png-to-webp,jpg-to-webp,gif-to-webp (max 20).

Questions or issues? Contact [email protected]

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Henderson-Hasselbalch Equation (pH / HCO₃⁻ / PCO₂)

json· JSON resultOpen tool

Name

Type

Required

Description

number

Arterial pH. Provide any TWO of pH / HCO₃⁻ / PaCO₂; the tool solves the third. If all three are provided, the tool checks Henderson-Hasselbalch consistency instead.

hco3

number

Bicarbonate (mmol/L). Provide any TWO of pH / HCO₃⁻ / PaCO₂.

paco2

number

Arterial PaCO₂ (mmHg). Provide any TWO of pH / HCO₃⁻ / PaCO₂.

decimalPlaces

number

—

{ "mcpServers": { "elysiatools-bicarbonate-ph-conversion": { "name": "bicarbonate-ph-conversion", "description": "Solve any one of pH/HCO₃⁻/PaCO₂ from the other two via pH = 6.1 + log10(HCO₃⁻/(0.03×PaCO₂)). Reports linear Henderson [H⁺] cross-check. Derived from Henderson 1908, Hasselbalch 1916, Siggaard-Andersen 1974, LITFL, StatPearls, Berend 2016. Not medical advice.", "baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=bicarbonate-ph-conversion", "command": "", "args": [], "env": {}, "isActive": true, "type": "sse" } } }

{ "jsonrpc": "2.0", "id": 2, "method": "tools/call", "params": { "name": "bicarbonate-ph-conversion", "arguments": { "ph": 0, "hco3": 24, "paco2": 40, "decimalPlaces": 2 } } }