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Estimate creatinine clearance (CrCl) with the Cockcroft-Gault equation: CrCl (mL/min) = [(140 − Age) × Weight(kg)] / [72 × SCr(mg/dL)] × 0.85 if female. Choose the weight basis: Actual Body Weight (ABW), Ideal Body Weight (IBW, Devine 1974), or Adjusted Body Weight (AdjBW = IBW + 0.4 × (ABW − IBW), for obese patients). Optional SCr floor at 1.0 mg/dL for elderly / low-muscle-mass patients. Returns an UN-indexed CrCl in mL/min — the value drug-dosing tables use (for BSA-indexed eGFR use MDRD or CKD-EPI). Derived from Cockcroft & Gault, Nephron 1976. Valid for stable renal function in adults. Not medical advice.
Execution
Fill in the form, run the tool, and review the result in one place.
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Tool usage guide
Estimate unindexed creatinine clearance (CrCl) in mL/min with the Cockcroft-Gault equation for adults with stable renal function. Enter age, sex, actual body weight, serum creatinine, and select ABW, IBW, or AdjBW as the weight basis.
Background
A 70-year-old male has an actual body weight of 75 kg and serum creatinine of 1.0 mg/dL.
Problem
Calculate creatinine clearance using Actual Body Weight.
How to use
Enter age 70, select Male, enter weight 75 kg and serum creatinine 1.0 mg/dL, then select ABW.
Outcome
The calculator returns CrCl = 72.9167 mL/min using ABW, with serum creatinine of 1.0 mg/dL.
Background
A 55-year-old female weighs 60 kg, is 160 cm tall, and has serum creatinine of 0.9 mg/dL.
Problem
Calculate CrCl using Devine Ideal Body Weight rather than actual body weight.
How to use
Enter age 55, select Female, enter weight 60 kg, height 160 cm, serum creatinine 0.9 mg/dL, and select IBW.
Outcome
The calculator uses an IBW of 52.3819 kg and returns CrCl = 58.4042 mL/min.
It uses the Cockcroft-Gault equation: CrCl = [(140 − age) × weight] / [72 × serum creatinine], multiplied by 0.85 for females.
You can select Actual Body Weight, Ideal Body Weight using the Devine formula, or Adjusted Body Weight.
Height is required when using Ideal Body Weight or Adjusted Body Weight. It is not required for Actual Body Weight.
When selected, serum creatinine values below 1.0 mg/dL are treated as 1.0 mg/dL.
No. The result is an unindexed CrCl in mL/min, not a BSA-indexed eGFR.