Caprini Score (VTE Risk, 2005)

Calculate base excess (BE) using the Siggaard-Andersen formula. BE < −3 metabolic acidosis, > +3 metabolic alkalosis. HCO₃⁻ auto-calculated from pH + PaCO₂ if omitted. Derived from Siggaard-Andersen 1974, Cornell PICU, Medscape, and Langer 2022. Not medical advice.

Complete ABG analysis: pH, primary disorder, compensation (Winter's formula), anion gap ± albumin correction, delta ratio for mixed disorder detection. Derived from Emmett 2016, Kraut 2007, Rastegar 2007, LITFL, MDCalc, and Adrogué 1998. Not medical advice.

Calculate the CHA₂DS₂-VASc score to stratify stroke risk in non-valvular atrial fibrillation and guide oral anticoagulation. Components: Congestive heart failure/LV dysfunction (+1), Hypertension (+1), Age ≥75 (+2), Diabetes (+1), prior Stroke/TIA/thromboembolism (+2), Vascular disease — prior MI/PAD/aortic plaque (+1), Age 65–74 (+1), Sex category female (+1). Range 0–9 (women) / 0–8 (men). Thresholds: men ≥2 or women ≥3 → recommend oral anticoagulation (DOAC preferred over warfarin); men 1 or women 2 → consider anticoagulation; men 0 or women ≤1 → omit. Female sex alone is not an independent risk factor (score 1 from sex alone is treated as 0). Includes an approximate annual stroke-risk estimate (Lip 2010 derivation cohort). Derived from Lip 2010 (Chest), 2019 AHA/ACC/HRS update, and 2023 ACC/AHA/ACCP/HRS AF guideline. Combine with bleeding risk (HAS-BLED) and shared decision-making. Not medical advice.

Calculate the Charlson Comorbidity Index (CCI), including the age-adjusted variant, to predict 1-year mortality from chronic comorbidities. 19 comorbidities are weighted by mortality risk: 1 point (MI, CHF, PVD, cerebrovascular disease, dementia, chronic pulmonary disease, connective tissue disease, peptic ulcer, mild liver disease, diabetes without complications); 2 points (hemiplegia/paraplegia, moderate-to-severe CKD, diabetes with end-organ damage, any non-metastatic tumor, leukemia, lymphoma); 3 points (moderate-to-severe liver disease); 6 points (metastatic solid tumor, AIDS). Age adjustment adds 1 point per decade ≥50 (50-59 +1 … ≥90 +5). Interpretation: 0 ~8%, 1-2 ~25%, 3-4 ~50%, ≥5 ~80-90% 1-year mortality (derivation cohort). Derived from Charlson 1987 (J Chronic Dis) and the 1994 validation. Not medical advice.