Calculate the Urea Reduction Ratio (URR) for a single hemodialysis session: URR (%) = (Pre-BUN − Post-BUN) / Pre-BUN × 100. KDOQI recommends a minimum URR ≥65% and a target dose ≥70%. URR is a simple adequacy marker but is being phased out in favor of Kt/V, which also accounts for urea generation and volume contraction. Derived from the KDOQI Clinical Practice Guideline for Hemodialysis Adequacy. Valid for single hemodialysis sessions with BUN drawn pre- and immediately post-treatment; not for peritoneal dialysis. Not medical advice.
Execution
Run this tool
Fill in the form, run the tool, and review the result in one place.
Samples
Examples that match this tool
Related
Continue with connected tools and hubs
Result
Ready for a run
Run the tool to preview files, text, structured data, or streamed output here.
Tool usage guide
Learn when to use this tool, what it supports, and how real users apply it.
Key facts
Category
Health
Input types
number
Output type
json
Sample coverage
4
API ready
Yes
Overview
Calculate the Urea Reduction Ratio (URR) for one hemodialysis session using pre-dialysis and post-dialysis BUN values. The calculator applies URR = (Pre-BUN − Post-BUN) / Pre-BUN × 100% and compares the result with KDOQI reference thresholds of 65% minimum and 70% target. This tool is not medical advice.
When to use
Estimate URR for a single hemodialysis session with BUN measured before and immediately after treatment.
Check whether a calculated URR reaches the KDOQI minimum of 65% or target of 70%.
Review a simple dialysis adequacy marker before confirming adequacy with Kt/V and clinical judgment.
How it works
1Enter the pre-dialysis BUN in mg/dL.
2Enter the post-dialysis BUN in mg/dL; it must be at least 0 and lower than the pre-dialysis value.
3The calculator subtracts post-BUN from pre-BUN, divides by pre-BUN, and multiplies by 100.
4The JSON result includes the URR percentage, unit, status, calculation method, and a note about the KDOQI thresholds.
Use cases
Dialysis staff can calculate and document the URR from pre- and post-treatment BUN measurements.
Nephrology learners can verify the URR formula and compare sample results with KDOQI thresholds.
Clinical reviewers can quickly identify results below the 65% minimum for further assessment.
Examples
1. URR reaches the target threshold
Dialysis clinician
Background
A single hemodialysis session has a pre-dialysis BUN of 90 mg/dL and a post-dialysis BUN of 27 mg/dL.
Problem
Calculate the percentage reduction and determine whether it meets the KDOQI target.
How to use
Enter 90 for Pre-dialysis BUN, 27 for Post-dialysis BUN, and use 4 decimal places.
{"preBun":90,"postBun":27,"decimalPlaces":4}
Outcome
The calculator returns URR = 70.0000%, with the status Target met (≥70%).
2. URR falls below the minimum threshold
Nephrology student
Background
A hemodialysis session has a pre-dialysis BUN of 80 mg/dL and a post-dialysis BUN of 30 mg/dL.
Problem
Check whether the calculated URR meets the minimum KDOQI reference value.
How to use
Enter 80 for Pre-dialysis BUN, 30 for Post-dialysis BUN, and use 4 decimal places.
FAQ
What is the URR formula?
URR (%) = (Pre-BUN − Post-BUN) / Pre-BUN × 100.
What URR value is considered adequate?
The referenced KDOQI thresholds are a minimum of 65% and a target of 70% or higher.
What inputs does this calculator require?
It requires pre-dialysis BUN and post-dialysis BUN values in mg/dL. Decimal places are optional.
Can I use URR for peritoneal dialysis?
No. This calculator is intended for a single hemodialysis session.
Is URR a replacement for Kt/V?
No. URR is a simple marker and does not account for urea generation or volume contraction; Kt/V should be used to confirm full adequacy.