Education

Wright–Fisher Population Drift & Allele Frequency Tutor

Simulate Wright–Fisher genetic drift across many replicate populations with mutation and selection. Visualize drift trajectories, the final-frequency distribution, heterozygosity decay Hₜ = H₀(1−1/2Nₑ)ᵗ, and run a Hardy–Weinberg chi-square test.

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Quick start

Call this tool from your code in three languages.

cURL

curl -X POST 'https://api.elysiatools.com/en/api/tools/wright-fisher-population-drift-and-allele-frequency-tutor' \
  -H 'Content-Type: application/json' \
  -d '{"N":100,"ploidy":"diploid","generations":100,"reps":40,"p0":0.5,"mu":0,"s":0,"dominance":"additive","seed":42,"hwAA":0,"hwAa":0,"hwaa":0}'

API reference

Send a POST request with your inputs as JSON. File parameters require a separate upload first.

Endpoint

HTTP

POST https://api.elysiatools.com/en/api/tools/wright-fisher-population-drift-and-allele-frequency-tutor

Parameters

Name	Type	Required	Description
N	number	No	—
ploidy	select	No	—
generations	number	No	—
reps	number	No	—
p0	number	No	—
mu

MCP integration

Add this tool to your Model Context Protocol server so AI agents can list and call it.

Server configuration

Add this block to your MCP client configuration:

mcp.json

{
  "mcpServers": {
    "elysiatools-wright-fisher-population-drift-and-allele-frequency-tutor": {
      "name": "wright-fisher-population-drift-and-allele-frequency-tutor",
      "description": "Simulate Wright–Fisher genetic drift across many replicate populations with mutation and selection. Visualize drift trajectories, the final-frequency distribution, heterozygosity decay Hₜ = H₀(1−1/2Nₑ)ᵗ, and run a Hardy–Weinberg chi-square test.",
      "baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=wright-fisher-population-drift-and-allele-frequency-tutor",
      "command": "",
      "args": [],
      "env": {},
      "isActive": true,
      "type": "sse"
    }
  }
}

List available tools

After connecting to the SSE endpoint, list the exposed tools:

tools/list

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/list"
}

Call this tool

Invoke the tool by its id, passing arguments built from its parameters:

tools/call

{
  "jsonrpc": "2.0",
  "id": 2,
  "method": "tools/call",
  "params": {
    "name": "wright-fisher-population-drift-and-allele-frequency-tutor",
    "arguments": {
  "N": 100,
  "ploidy": "diploid",
  "generations": 100,
  "reps": 40,
  "p0": 0.5,
  "mu": 0,
  "s": 0,
  "dominance": "additive",
  "seed": 42,
  "hwAA": 0,
  "hwAa": 0,
  "hwaa": 0
}
  }
}

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