Health
Warfarin Dose Adjustment Calculator (INR Nomogram)
Adjust warfarin maintenance dose from the current INR using the standard nomogram for a target INR of 2.0–3.0. No-bleed ladder: INR<1.5 → +10–20% weekly dose; 1.5–1.9 → +5–15%; 2.0–3.0 → no change; 3.1–3.5 → −5–15%; 3.6–4.0 → −10–20%; 4.1–4.4 → hold 0–1 dose, ~−20%; 4.5–10 → hold + oral vitamin K₁ 1–2.5 mg; >10 → hold + oral vitamin K₁ 2.5–5 mg. Serious/life-threatening bleed at any INR → hold warfarin, vitamin K₁ 5–10 mg IV (slow, 20–30 min) + 4-factor PCC (FFP if unavailable). Optional current weekly dose computes the concrete new weekly and daily dose. Derived from the 9th-edition ACCP Guidelines (Holbrook et al., Chest 2012) and the UW Anticoagulation Clinic nomogram. Valid for adult maintenance therapy at steady state; not for initial induction, DOAC/heparin overlap, or perioperative bridging. Not medical advice.
Quick start
Call this tool from your code in three languages.
curl -X POST 'https://api.elysiatools.com/en/api/tools/warfarin-dose-adjustment' \
-H 'Content-Type: application/json' \
-d '{"inr":1.7,"weeklyDose":35,"seriousBleed":false,"decimalPlaces":4}'API reference
Send a POST request with your inputs as JSON. File parameters require a separate upload first.
Endpoint
POST https://api.elysiatools.com/en/api/tools/warfarin-dose-adjustmentParameters
| Name | Type | Required | Description |
|---|---|---|---|
| inr | number | Yes | Current INR (prothrombin time ratio). Must be positive. |
| weeklyDose | number | No | Optional current total weekly warfarin dose in mg. Used to compute the new concrete weekly/daily dose. |
| seriousBleed | checkbox | No | If checked, the tool switches to the full-reversal pathway (hold + IV vitamin K₁ + PCC) regardless of INR. |
| decimalPlaces | number | No | — |
Response format
JSON result
MCP integration
Add this tool to your Model Context Protocol server so AI agents can list and call it.
Server configuration
Add this block to your MCP client configuration:
{
"mcpServers": {
"elysiatools-warfarin-dose-adjustment": {
"name": "warfarin-dose-adjustment",
"description": "Adjust warfarin maintenance dose from the current INR using the standard nomogram for a target INR of 2.0–3.0. No-bleed ladder: INR<1.5 → +10–20% weekly dose; 1.5–1.9 → +5–15%; 2.0–3.0 → no change; 3.1–3.5 → −5–15%; 3.6–4.0 → −10–20%; 4.1–4.4 → hold 0–1 dose, ~−20%; 4.5–10 → hold + oral vitamin K₁ 1–2.5 mg; >10 → hold + oral vitamin K₁ 2.5–5 mg. Serious/life-threatening bleed at any INR → hold warfarin, vitamin K₁ 5–10 mg IV (slow, 20–30 min) + 4-factor PCC (FFP if unavailable). Optional current weekly dose computes the concrete new weekly and daily dose. Derived from the 9th-edition ACCP Guidelines (Holbrook et al., Chest 2012) and the UW Anticoagulation Clinic nomogram. Valid for adult maintenance therapy at steady state; not for initial induction, DOAC/heparin overlap, or perioperative bridging. Not medical advice.",
"baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=warfarin-dose-adjustment",
"command": "",
"args": [],
"env": {},
"isActive": true,
"type": "sse"
}
}
}List available tools
After connecting to the SSE endpoint, list the exposed tools:
{
"jsonrpc": "2.0",
"id": 1,
"method": "tools/list"
}Call this tool
Invoke the tool by its id, passing arguments built from its parameters:
{
"jsonrpc": "2.0",
"id": 2,
"method": "tools/call",
"params": {
"name": "warfarin-dose-adjustment",
"arguments": {
"inr": 1.7,
"weeklyDose": 35,
"seriousBleed": false,
"decimalPlaces": 4
}
}
}