Health

Mean Platelet Volume (MPV) Analyzer

Analyze Mean Platelet Volume (MPV) in fL, an index of platelet production kinetics. Reference range ≈ 7.5–11.5 fL (lab- and method-dependent). Low MPV (< 7.5 fL, small old platelets) indicates suppressed marrow production (aplastic anemia, chemotherapy/radiation, recent platelet transfusion, iron-deficiency regeneration, Wiskott-Aldrich). High MPV (> 11.5 fL, large young platelets) indicates peripheral destruction with compensatory turnover or macrothrombocytopenia (immune thrombocytopenia ITP, post-splenectomy, myeloproliferative neoplasms, severe sepsis in recovery, Bernard-Soulier / MYH9, megaloblastic anemia; elevated MPV after acute MI marks platelet activation and adverse prognosis). Optionally enter the platelet count to refine the differential: low platelets + high MPV → peripheral destruction; low + low → underproduction; high + low → reactive thrombocytosis; high + high → myeloproliferative neoplasm. Pre-analytical caveat: platelets swell in EDTA over ~2 h raising MPV, and values are method-dependent (impedance > optical > immuno) — compare within the same lab and analyzer. Derived from Bath 1996, Leader 2012, Vagdatli 2010, and MDCalc. Not medical advice.

json· JSON resultOpen tool

Quick start

Call this tool from your code in three languages.

cURL

curl -X POST 'https://api.elysiatools.com/en/api/tools/mean-platelet-volume-analyzer' \
  -H 'Content-Type: application/json' \
  -d '{"mpv":12.5,"plateletCount":45,"decimalPlaces":1}'

API reference

Send a POST request with your inputs as JSON. File parameters require a separate upload first.

Endpoint

HTTP

POST https://api.elysiatools.com/en/api/tools/mean-platelet-volume-analyzer

Parameters

Name	Type	Required	Description
mpv	number	Yes	Mean platelet volume reported by the hematology analyzer, in femtolitres (fL).
plateletCount	number	No	Optional platelet count in ×10⁹/L. When provided, the interpretation is refined using the MPV/platelet-count pairing.
decimalPlaces	number	No	—

Response format

JSON result

JSON

{
  "key": {...},
  "metadata": {
    "key": "value"
  },
  "error": "Error message (optional)",
  "message": "Notification message (optional)"
}

MCP integration

Add this tool to your Model Context Protocol server so AI agents can list and call it.

Server configuration

Add this block to your MCP client configuration:

mcp.json

{
  "mcpServers": {
    "elysiatools-mean-platelet-volume-analyzer": {
      "name": "mean-platelet-volume-analyzer",
      "description": "Analyze Mean Platelet Volume (MPV) in fL, an index of platelet production kinetics. Reference range ≈ 7.5–11.5 fL (lab- and method-dependent). Low MPV (< 7.5 fL, small old platelets) indicates suppressed marrow production (aplastic anemia, chemotherapy/radiation, recent platelet transfusion, iron-deficiency regeneration, Wiskott-Aldrich). High MPV (> 11.5 fL, large young platelets) indicates peripheral destruction with compensatory turnover or macrothrombocytopenia (immune thrombocytopenia ITP, post-splenectomy, myeloproliferative neoplasms, severe sepsis in recovery, Bernard-Soulier / MYH9, megaloblastic anemia; elevated MPV after acute MI marks platelet activation and adverse prognosis). Optionally enter the platelet count to refine the differential: low platelets + high MPV → peripheral destruction; low + low → underproduction; high + low → reactive thrombocytosis; high + high → myeloproliferative neoplasm. Pre-analytical caveat: platelets swell in EDTA over ~2 h raising MPV, and values are method-dependent (impedance > optical > immuno) — compare within the same lab and analyzer. Derived from Bath 1996, Leader 2012, Vagdatli 2010, and MDCalc. Not medical advice.",
      "baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=mean-platelet-volume-analyzer",
      "command": "",
      "args": [],
      "env": {},
      "isActive": true,
      "type": "sse"
    }
  }
}

List available tools

After connecting to the SSE endpoint, list the exposed tools:

tools/list

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/list"
}

Call this tool

Invoke the tool by its id, passing arguments built from its parameters:

tools/call

{
  "jsonrpc": "2.0",
  "id": 2,
  "method": "tools/call",
  "params": {
    "name": "mean-platelet-volume-analyzer",
    "arguments": {
  "mpv": 12.5,
  "plateletCount": 45,
  "decimalPlaces": 1
}
  }
}