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Thyroid Index (TSH/FT4/FT3 Interpretation)

Interpret the thyroid axis by pattern-reading TSH with FT4 and (optionally) FT3. Adult reference ranges: TSH 0.4–4.0 mIU/L, FT4 0.8–1.8 ng/dL (≈10–23 pmol/L), FT3 2.3–4.2 pg/mL (≈3.5–6.5 pmol/L). High TSH + low FT4 → overt primary hypothyroidism; high TSH + normal FT4 → subclinical hypothyroidism; low TSH + high FT4/FT3 → overt primary hyperthyroidism; low TSH + normal FT4 → subclinical hyperthyroidism, exogenous hormone, or resolving thyroiditis (check FT3 for T3 toxicosis); low/normal TSH + low FT4 → central hypothyroidism; high TSH + high FT4 → TSH-secreting adenoma or thyroid hormone resistance. Low FT3 with normal TSH/FT4 indicates low-T3 (non-thyroidal illness) syndrome. Units selectable for TSH, FT4, FT3. Derived from ATA 2014/2016, NACB 2002, Garber 2012, and MDCalc. Not medical advice.

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Quick start

Call this tool from your code in three languages.

cURL
curl -X POST 'https://api.elysiatools.com/en/api/tools/thyroid-index' \
  -H 'Content-Type: application/json' \
  -d '{"tshUnit":"miu","ft4Unit":"ngdl","ft3Unit":"pgml","tsh":12,"ft4":0.5,"ft3":0,"decimalPlaces":2}'

API reference

Send a POST request with your inputs as JSON. File parameters require a separate upload first.

Endpoint

HTTP
POST https://api.elysiatools.com/en/api/tools/thyroid-index

Parameters

NameTypeRequiredDescription
tshUnitselectYes—
ft4UnitselectYes—
ft3UnitselectYes—
tshnumberYesThyrotropin (TSH). Unit selected under 'TSH Unit' (mIU/L or µIU/mL; numerically equivalent).
ft4numberYesFree T4. Unit selected under 'FT4 Unit' (ng/dL or pmol/L).

MCP integration

Add this tool to your Model Context Protocol server so AI agents can list and call it.

Server configuration

Add this block to your MCP client configuration:

mcp.json
{
  "mcpServers": {
    "elysiatools-thyroid-index": {
      "name": "thyroid-index",
      "description": "Interpret the thyroid axis by pattern-reading TSH with FT4 and (optionally) FT3. Adult reference ranges: TSH 0.4–4.0 mIU/L, FT4 0.8–1.8 ng/dL (≈10–23 pmol/L), FT3 2.3–4.2 pg/mL (≈3.5–6.5 pmol/L). High TSH + low FT4 → overt primary hypothyroidism; high TSH + normal FT4 → subclinical hypothyroidism; low TSH + high FT4/FT3 → overt primary hyperthyroidism; low TSH + normal FT4 → subclinical hyperthyroidism, exogenous hormone, or resolving thyroiditis (check FT3 for T3 toxicosis); low/normal TSH + low FT4 → central hypothyroidism; high TSH + high FT4 → TSH-secreting adenoma or thyroid hormone resistance. Low FT3 with normal TSH/FT4 indicates low-T3 (non-thyroidal illness) syndrome. Units selectable for TSH, FT4, FT3. Derived from ATA 2014/2016, NACB 2002, Garber 2012, and MDCalc. Not medical advice.",
      "baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=thyroid-index",
      "command": "",
      "args": [],
      "env": {},
      "isActive": true,
      "type": "sse"
    }
  }
}

List available tools

After connecting to the SSE endpoint, list the exposed tools:

tools/list
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/list"
}

Call this tool

Invoke the tool by its id, passing arguments built from its parameters:

tools/call
{
  "jsonrpc": "2.0",
  "id": 2,
  "method": "tools/call",
  "params": {
    "name": "thyroid-index",
    "arguments": {
  "tshUnit": "miu",
  "ft4Unit": "ngdl",
  "ft3Unit": "pgml",
  "tsh": 12,
  "ft4": 0.5,
  "ft3": 0,
  "decimalPlaces": 2
}
  }
}
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ft3numberNoOptional free T3. Unit selected under 'FT3 Unit' (pg/mL or pmol/L). Used to detect T3 toxicosis and low-T3 syndrome.
decimalPlacesnumberNo—

Response format

JSON result

JSON
{
  "key": {...},
  "metadata": {
    "key": "value"
  },
  "error": "Error message (optional)",
  "message": "Notification message (optional)"
}
Chain multiple tools in one session with a comma-separated toolId list, e.g. /mcp/sse?toolId=png-to-webp,jpg-to-webp,gif-to-webp (max 20).

Questions or issues? Contact [email protected]