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Dosing Interval Designer (Peak/Trough Ratio)

Design the dosing interval τ from the steady-state peak/trough concentration ratio. For one-compartment linear kinetics at steady state, the peak-to-trough ratio over one interval is P = Cmax,ss / Cmin,ss = e^(kτ) where k = ln2 / t½. Mode A: given a target peak/trough ratio, solve for the dosing interval τ = ln(P) · t½ / ln2. Mode B: given a chosen interval τ, compute the resulting peak/trough ratio P = e^(kτ). Note: P reflects fluctuation WITHIN one interval and is NOT the accumulation index (R = 1/(1-e^(-kτ))). Valid only for linear one-compartment kinetics, steady state, fixed dose and interval. Not medical advice.

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Quick start

Call this tool from your code in three languages.

cURL
curl -X POST 'https://api.elysiatools.com/en/api/tools/dosing-interval-designer' \
  -H 'Content-Type: application/json' \
  -d '{"mode":"ratio-to-tau","halfLife":6,"ratio":4,"interval":0,"decimalPlaces":4}'

API reference

Send a POST request with your inputs as JSON. File parameters require a separate upload first.

Endpoint

HTTP
POST https://api.elysiatools.com/en/api/tools/dosing-interval-designer

Parameters

NameTypeRequiredDescription
modeselectNo—
halfLifenumberYesElimination half-life. Must be positive.
rationumberNoTarget peak/trough ratio. Required in mode A. Must be >1 (peak exceeds trough).
intervalnumberNoChosen dosing interval. Required in mode B. Must be positive.
decimalPlacesnumberNo

MCP integration

Add this tool to your Model Context Protocol server so AI agents can list and call it.

Server configuration

Add this block to your MCP client configuration:

mcp.json
{
  "mcpServers": {
    "elysiatools-dosing-interval-designer": {
      "name": "dosing-interval-designer",
      "description": "Design the dosing interval τ from the steady-state peak/trough concentration ratio. For one-compartment linear kinetics at steady state, the peak-to-trough ratio over one interval is P = Cmax,ss / Cmin,ss = e^(kτ) where k = ln2 / t½. Mode A: given a target peak/trough ratio, solve for the dosing interval τ = ln(P) · t½ / ln2. Mode B: given a chosen interval τ, compute the resulting peak/trough ratio P = e^(kτ). Note: P reflects fluctuation WITHIN one interval and is NOT the accumulation index (R = 1/(1-e^(-kτ))). Valid only for linear one-compartment kinetics, steady state, fixed dose and interval. Not medical advice.",
      "baseUrl": "https://api.elysiatools.com/mcp/sse?toolId=dosing-interval-designer",
      "command": "",
      "args": [],
      "env": {},
      "isActive": true,
      "type": "sse"
    }
  }
}

List available tools

After connecting to the SSE endpoint, list the exposed tools:

tools/list
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/list"
}

Call this tool

Invoke the tool by its id, passing arguments built from its parameters:

tools/call
{
  "jsonrpc": "2.0",
  "id": 2,
  "method": "tools/call",
  "params": {
    "name": "dosing-interval-designer",
    "arguments": {
  "mode": "ratio-to-tau",
  "halfLife": 6,
  "ratio": 4,
  "interval": 0,
  "decimalPlaces": 4
}
  }
}
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© 2026 Elysia Tools. Developer documentation.

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Response format

JSON result

JSON
{
  "key": {...},
  "metadata": {
    "key": "value"
  },
  "error": "Error message (optional)",
  "message": "Notification message (optional)"
}
Chain multiple tools in one session with a comma-separated toolId list, e.g. /mcp/sse?toolId=png-to-webp,jpg-to-webp,gif-to-webp (max 20).

Questions or issues? Contact [email protected]