# TPN Macronutrient Calculator (Glucose/AA/Lipid) Calculate glucose/amino-acid/lipid delivery (grams and kcal), total and non-protein calories, the non-protein kcal:g nitrogen ratio and per-kg values from a parenteral nutrition prescription. Energy densities: dextrose 3.4 kcal/g, AA 4.0 kcal/g, lipid 20% ≈ 2.0 kcal/mL. Targets (ASPEN/ESPEN): 20–30 kcal/kg/day, protein 1.0–1.5 g/kg/day. This is a prescription-analysis aid, not a compounding recipe. Derived from ASPEN 2016, ESPEN 2019, McClave 2016, Mirtallo 2004. Not medical advice. > Canonical page: https://elysiatools.com/en/tools/tpn-macronutrient-calculator - **Category:** Health - **Keywords:** TPN, total parenteral nutrition, parenteral nutrition, macronutrient, dextrose, amino acid, lipid emulsion, non-protein calories, nitrogen ratio, nutrition support, critical care, pharmacy ## Overview The TPN Macronutrient Calculator analyzes a parenteral nutrition prescription using patient weight, dextrose and amino-acid concentrations and volumes, lipid emulsion selection, and lipid volume. It estimates macronutrient grams, calories, total and non-protein calories, nitrogen-related ratios, and per-kilogram values. This is a prescription-analysis aid, not a compounding recipe or medical advice. ## Inputs - **Patient weight (kg)** (number): Patient weight in kg — used for per-kg kcal, protein, glucose-infusion-rate and lipid ceilings. - **Dextrose concentration (%)** (number): Dextrose concentration % w/v. D25W = 25 g/100 mL. - **Dextrose volume (mL)** (number): Total dextrose volume (mL). - **Amino acid concentration (%)** (number): Amino-acid concentration % w/v. AA 8.5% = 8.5 g/100 mL. - **Amino acid volume (mL)** (number): Total amino-acid volume (mL). - **Lipid emulsion** (select) - **Lipid volume (mL)** (number): Total lipid emulsion volume (mL). - **Decimal Places** (number) ## When to use - Review the calorie and protein contribution of a proposed TPN prescription. - Compare dextrose, amino-acid, and lipid delivery on a per-kilogram basis. - Check total calories, non-protein calories, and the non-protein kcal:g nitrogen ratio. ## How it works - Enter the patient weight in kilograms. - Enter the dextrose and amino-acid concentrations and total volumes. - Select the lipid emulsion concentration and enter its total volume. - The calculator estimates grams, kcal, total and non-protein calories, nitrogen-related values, ratios, and per-kilogram results. ## Use cases - Clinical nutrition review of adult parenteral nutrition prescriptions. - Pharmacy and nutrition-support checks of macronutrient and calorie delivery. - Education on how dextrose, amino acids, lipids, and patient weight affect TPN calculations. ## Frequently asked questions ### What inputs does the calculator require? It requires patient weight, dextrose concentration and volume, amino-acid concentration and volume, lipid emulsion type, and lipid volume. ### Which lipid emulsion concentrations are supported? The calculator supports 10%, 20%, and 30% lipid emulsions. ### How are dextrose calories estimated? Dextrose is estimated at 3.4 kcal per gram. ### How are amino-acid calories estimated? Amino acids are estimated at 4.0 kcal per gram. ### Can this tool be used as a compounding recipe? No. It analyzes prescription inputs and is not a compounding recipe or a substitute for clinical review. ## Related tools - [Milliequivalent Converter (mEq ↔ mg / mmol)](https://elysiatools.com/en/tools/milliequivalent-converter): Convert mEq ↔ mg/mmol (or mEq/L ↔ mmol/L, mg/L) from molecular weight and valence: mEq = mmol × valence, mg = mmol × MW. 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